The researchers examined the brains of 19 people who died anywhere from several hours to two months after reporting symptoms. They ranged in age from five to 73 years old.
"Some were found dead in bed by their partner or spouse, some were found dead in a nursing home, one guy was found dead on a subway," Nath explained.
Nath said he was surprised to find almost all of the patients had abnormalities in the brain.
He said bright spots visible on their brain scans represented areas of inflammation. Dark spots represented bleeding in the brain, which Nath said was likely a result of blood vessels leaking.
"If these patients had survived, let's say, could they have had long-term consequences? And the answer is yes. If you've got that kind of pathology in the brain, you've got damage to the brain," Nath explained.
Nath said he did not discover any signs of COVID-19 in the brain tissue itself, suggesting the damage was not caused by a direct viral attack on the brain, but instead came from the body's inflammatory response to the virus.
"When I sit back sometimes and think about it, I'm just shocked at what this virus does to us," said Dr. Farha Ikramuddin, a physical medicine rehabilitation physician at M Health Fairview and assistant professor at the University of Minnesota Medical School.
Dr. ikramuddin works firsthand with so-called 'COVID long-haulers,' people who have mysterious, lingering symptoms long after recovering from the virus.
"Anywhere from impaired cognition such as not being able to remember things to absolute hallucinations and delirium to death. I have seen a few patients with what we can fantasmia, which is basically hallucinations of smell, so they smell things that are not there," Ikramuddin explained. "Patients do not need to be admitted to the hospital to have significant post-COVID-19 syndrome."
Ikramuddin believes it is extremely important to keep looking at the brain, in an effort to understand COVID-19 symptoms and outcomes.
The National Institutes of Health recently launched a new Neuro-COVID Project, which will allow doctors across the country to send data and specimens to a central databank/biobank, in the hopes of tracking neurological symptoms associated with the virus:
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February 16, 2021 at 08:33AM
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New study shows some COVID-19 patients end up with damage to brains - KSTP
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